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KMID : 1234920200200010020
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Journal of Korean Oriental Association for Study of Obesity
2020 Volume.20 No. 1 p.20 ~ p.30
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The Retrospective Analysis of Effects of H Gambitang (GB-001) on Weight Loss in Pre- and Post-Menopausal Obese Woman
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Cho Hong-Seok
Seo Yeon-Ho
Kim Koh-Woon
Cho Jae-Heung
Song Mi-Yeon
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Abstract
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Objectives: The purpose of this study is to verify the effects of H Gambitang (GB-001) on body composition and basal metabolic rate in pre- and post-menopausal obese woman retrospectively.
Methods: The study was conducted on 57 middle-aged obese women. They were divided into two groups; pre-menopausal obesity group (Pr-MOG; n=34) and post-menopausal obesity group (Po-MOG; amenorrhea was continued to 14~48 month, n=23) with no significant difference of age, height, body weight and body mass index. All subjects took herbal medicine 3 times a day, for 6 weeks during treatment period. The weight, height, body fat mass, skeletal muscle mass, and basal metabolic rate of all subjects were measured on first visit. The following measurements were repeated after 2 weeks (2nd), 4 weeks (3rd) and 6 weeks (4th) with Inbody 370 (Biospace) equipment to identify changes of body fat mass, skeletal muscle mass, and basal metabolic rate. Results are represented as mean and standard deviation.
Results: Po-MOG showed significantly lower decrease rate in weight reduction on 2~6 weeks while significantly higher decrease rate in skeletal muscle reduction on 4~6 weeks. There were no significant differences between two groups in body fat reduction rate and basal metabolic increasing rate.
Conclusions: H Gambitang (GB-001) can be used not only in Pr-MOG but in Po-MOG in weight loss although the effect can be lower in Po-MOG. To prevent skeletal muscle mass loss in Po-MOG, following study on adjusting dose and components of H Gambitang (GB-001) thought to be necessary.
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KEYWORD
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Menopause, Obesity, Herbal medicine
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